Do Akkermansia GLP-1 Supplements Work? What Trials Show

white supplement bottle with capsules spilled on a beige background

The Amazon listing for one popular Akkermansia capsule says it “Increases GLP-1 Production.” It’s a bold line, especially now that GLP-1 drugs are everywhere. But the human trials behind Akkermansia tell a narrower story, and the details matter if you’re deciding whether a $2-a-day capsule belongs in your routine. This article is for general informational … Read more

Does Black Pepper Really Boost Turmeric Absorption?

turmeric powder and black peppercorns in spoons on a marble table

There’s one number you see on turmeric supplement bottles and in ads again and again: black pepper makes curcumin absorb 2,000% better. It’s repeated so often that it feels like settled science. The original study is from 1998, though, and a newer independent trial found that adding the same black pepper compound did not help. … Read more

Your NAD+ Can Go Up 142%. Should You Feel Different?

checking a NAD+ supplement capsule label

Take a nicotinamide riboside supplement for eight weeks and your blood NAD+ level can climb by as much as 142%. That number is real, measured, and repeated across multiple clinical trials. What’s less clear is whether a higher number on a lab readout means you’ll actually feel, move, or age any differently. This post contains … Read more

Is Bryan Johnson’s Daily Vitamin Enough for His B12 Problem?

close-up of B12 supplement capsules

In May, biohacker Bryan Johnson announced he’d been diagnosed with autoimmune gastritis — a condition that stops his stomach from doing the two things it needs to do to absorb vitamin B12 normally. That’s a strange twist for someone whose supplement company sells a multivitamin built around, among other things, a very large dose of … Read more

Probiotic CFU Count: Does Higher Really Mean Better?

comparing probiotic supplement labels

Probiotic labels love to compete on one number: CFU count. But NIH’s own guidance says that number isn’t what determines whether a probiotic actually works — the specific strain is. Here’s what actually matters when you’re comparing two bottles on a shelf. This post contains affiliate links. If you make a purchase through them, we … Read more

Does Magnesium Lotion Really Absorb Through Your Skin?

applying magnesium lotion to leg for muscle relief

Magnesium oils and lotions are marketed as a way to get magnesium into your body without swallowing a pill. A peer-reviewed review of the science reached a blunt conclusion: the evidence for that claim is scientifically unsupported. Here’s what the research actually found, and whether that changes anything for the leg cramps or muscle aches … Read more